Wegovy
Semaglutide
by Novo Nordisk
Average 21% body weight loss — the gold standard in medically supervised weight loss
21%
Average body weight loss
STEP 1 trial, NEJM 2021
86%
Patients lost ≥5% body weight
STEP 1 trial, NEJM 2021
20%
Reduction in cardiovascular risk
SELECT trial, NEJM 2023
68 weeks
Duration of pivotal clinical trial
STEP 1 trial, NEJM 2021
How It Works
Mechanism of Action
Semaglutide mimics the hormone GLP-1, which is naturally released after eating. It works by slowing gastric emptying, reducing appetite signals in the brain, and improving insulin sensitivity — leading to significant, sustained caloric reduction without the feeling of deprivation.
Dosage Guide
Always follow your prescribing physician's specific instructions. The schedule below is a general guide.
Initiation dose — helps your body adjust, not a therapeutic dose
First escalation — most patients notice appetite reduction
Second escalation — significant weight loss typically begins
Third escalation — continued dose optimisation
Full maintenance dose — target weekly injection for long-term management
Key Benefits
Side Effects
Common Side Effects
- Nausea (particularly during dose escalation)
- Diarrhoea
- Vomiting
- Constipation
- Stomach pain
- Headache
- Fatigue
- Dizziness
Rare but Serious
- Pancreatitis
- Gallbladder disease
- Heart rate increase
- Kidney problems
- Allergic reactions
- Suicidal ideation (rare — report immediately)
Seek immediate medical attention if you experience any serious adverse effects.
Frequently Asked Questions
Who Is This For?
- Adults with BMI ≥30 kg/m²
- Adults with BMI ≥27 kg/m² with at least one weight-related condition (hypertension, type 2 diabetes, or dyslipidemia)
- Used alongside a reduced-calorie diet and increased physical activity
Not Suitable For
- Personal or family history of medullary thyroid carcinoma (MTC)
- Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
- Pregnancy or breastfeeding
- Known hypersensitivity to semaglutide
Starting from
$99.00
Reviewed by a licensed US physician
How It Works
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Ready to Start Your Wegovy Journey?
A licensed US physician will review your consultation, answer all your questions, and prescribe if you're eligible — all from the comfort of home.
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