Mounjaro
Tirzepatide
by Eli Lilly
Up to 22.5% body weight loss — the most effective weight loss medication in clinical history
22.5%
Maximum average weight loss (15mg dose)
SURMOUNT-1 trial, NEJM 2022
91%
Patients lost ≥5% body weight
SURMOUNT-1 trial, NEJM 2022
57%
Patients achieved ≥20% weight loss
SURMOUNT-1 trial, NEJM 2022
72 weeks
Duration of pivotal trial
SURMOUNT-1 trial, NEJM 2022
How It Works
Mechanism of Action
Tirzepatide activates both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. This dual-action approach amplifies satiety signals, slows digestion, reduces caloric intake, and improves metabolic efficiency in ways single-agonist medications cannot match.
Dosage Guide
Always follow your prescribing physician's specific instructions. The schedule below is a general guide.
Initiation dose — allows body to adjust to the medication
First maintenance dose — may be continued if tolerated well
Escalation — enhanced appetite suppression typically felt
Further dose increase for additional weight loss
Advanced dose — near maximum therapeutic effect
Maximum dose — highest efficacy for weight management
Key Benefits
Side Effects
Common Side Effects
- Nausea
- Diarrhoea
- Decreased appetite
- Vomiting
- Constipation
- Dyspepsia (indigestion)
- Abdominal pain
Rare but Serious
- Pancreatitis
- Gallstones
- Hypoglycaemia (particularly with diabetes medications)
- Injection site reactions
- Tachycardia
- Thyroid tumours (risk observed in animal studies)
Seek immediate medical attention if you experience any serious adverse effects.
Frequently Asked Questions
Who Is This For?
- Adults with BMI ≥30 kg/m²
- Adults with BMI ≥27 kg/m² with weight-related health conditions
- Adults with type 2 diabetes (as Mounjaro, lower doses)
- Alongside reduced-calorie diet and physical activity
Not Suitable For
- Personal or family history of MTC or MEN 2
- Pregnancy or planning pregnancy
- Severe gastrointestinal disease
- Known hypersensitivity to tirzepatide
Starting from
$176.00
Reviewed by a licensed US physician
How It Works
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Ready to Start Your Mounjaro Journey?
A licensed US physician will review your consultation, answer all your questions, and prescribe if you're eligible — all from the comfort of home.
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